The survey for the incidence of the greater wax moth, in bee colonies of Apis cerana in Karnataka revealed some degree of infestation in all the inspected colonies. Among the natural enemies of the wax moth, two entomopathogens, a nucleopolyhedrovirus (NPV) and a bacterium, and two larval parasitoids, Antrocephalus galleriae and Apanteles galleriae Wilkinson, were isolated. The parasitoids were more prevalent than the pathogens and seemed to keep the wax moth population under check. Studies on the cross infectivity of Galleria mellonella NPV to rice moth Corcyra cephalonica reveals the high susceptibility of C. cephalonica. When G. mellonella NPV was administered @1.7x106 POBs/ml, to the second instar larvae of mulberry silkworm Bombyx mori (KJ race) it did not cause any mortality to B. mori. Similarly the G. mellonella NPV was found to be safe to two species of honeybees viz., A. cerana and A. mellifera and also to a general predator Chryosoperla carnea. Parasites diseases and disorders; Parasites; Insect parasites; Hosts; Insect hosts; Diseases and disorders; Microbial diseases; Land zones; Oriental region; Eurasia; Asia; India Galleria mellonella (Pyralidae); Hymenopteran parasites; Antrocephalus galleriae & Apanteles galleriae; Records & prevalence; Bacterial diseases; Record & prevalence; Viral diseases; Nucleopolyhedrovirus; Record, prevalence & cross infectivity; Karnataka; Bacterial disease, viral disease & hymenopteran parasite records & prevalence, bee colonies Apanteles galleriae (Braconidae ); Antrocephalus galleriae (Chalcididae ); Lepidopteran hosts; Galleria mellnella; Records & prevalence; Karnataka; Records & prevalence in lepidopteran hosts, bee colonies none